http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2899694-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c5eb6598ba388a11ac7bb164309e1b2a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P23-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4425 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 |
| filingDate | 2013-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d3704b1d562525b9716051bf9cc63fdd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c4715e46530d74d1bc915a8909726b6a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7eef9dfe937d7718a5df9d35ffdd396c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7855403340c0b472e00a51947db086d |
| publicationDate | 2022-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2899694-T3 |
| titleOfInvention | Novel compounds, their synthesis and their uses |
| abstract | A new chemical compound of formula 1 **(See formula)** in which: Y is the DRUG-CO; the DRUG-OCO; the DRUG-NRCO, and X is selected from **(See formula)** with the exception that the modification can be carried out in more than one functional group of the DRUG, G- can be selected from iodide, chloride, bromide , mesylate, tosylate or tetrafluoroborate, or any other pharmaceutically acceptable anion; G- can be one or more opposite ions to balance the charge, R, R1 and R2 are independently H, straight or branched chain C1-C8 alkyl (optionally containing 1 to 3 heteroatoms selected from O, N, S, SO , or SO2; 3 to 7 membered cycloalkyl optionally containing 1 to 3 heteroatoms selected from O, N, S, SO, or SO2 and or lower alkyl, straight or branched alkyl, alkoxy; alkaryl, aryl, heteroaryl, or alkytaryl; or independently forms part of a 3 to 7 membered ring optionally containing 1 to 2 additional heteroatoms selected from O, N, S, SO, SO2 and may also be optionally substituted with alkoxy, F or Cl; wherein the chemical compound is selected from the group consisting of i.1-((2,6-diisopropylphenoxy)carbonyloxy)methyl)-3-(dimethylcarbamoyl)pyridinium mesylate; ii. 1-(((2,6-diisopropylphenoxy)carbonyloxy)methyl)-3-(methylcarbamoyl)pyridinium mesylate; iii. 3-carbamoyl-1-((2,6-diisopropylphenoxy)carbonyloxy)methyl)pyridinium mesylate; IV. 1-(((2,6-diisopropylphenoxy)carbonyloxy)methyl)-3-(methylcarbamoyl)pyridinium iodide; v. (E)-3-(dimethylcarbamoyl)-1-(((2-methoxy-4-((8-methylnon-6-enamido)methyl)phenoxy)carbonyloxy)methyl)pyridinium iodide; saw. (E)-3-(dimethylcarbamoyl)-1-((2-methoxy-4-((8-methylnon-6-enamido)methyl)phenoxy)carbonium)methyl)pyridinium mesylate; vii. 3-(dimethylamino)-1-((4-((1E,4Z,6E)-5-hydroxy-7-(4-hydroxy-3-methoxyphenyl)-3-oxohepta-1,4,6-trienyl iodide )-2-methoxyphenoxy)carbonyloxy)methyl)pyridinium; viii **(See formula)** xi. 1-((2-acetoxybenzoyloxy)methyl)-3-(methylcarbamoyl)pyridinium iodide; xii. 1-((2-acetoxybenzoyloxy)methyl)-3-(dimethylcarbamoyl)pyridinium iodide; xiii. 1-((2-acetoxybenzoyloxy)methyl)-3-carbamoylpyridinium mesylate; xiv. 1-((2-acetoxybenzoyloxy)methyl)-3-(dimethylcarbamoyl)pyridinium mesylate; xv. 1-((2-acetoxybenzoyloxy)methyl)-3-(methylcarbamoyl)pyridinium mesylate; xix. 1-((2-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetoxy)methyl)-3-(dimethylcarbamoyl)pyridinium iodide; xxiv. 1-((((6R,7R)-7-((E)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-(methoxymethyl)-8-oxo- 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carbonyl)oxy)methyl)-3-(dimethylcarbamoyl)pyridin-1-io; xxv. L(S)-1-((carboxymethyl)-4-methylpentylcarbamoyloxy)methyl)-3-(dimethylcarbamoyl)pyridinium methanesulfonate; xxvi. (S)-1-(carboxymethyl)-4-methylpentylcarbamoyloxy)methyl)-3-(dimethylcarbamoyl)pyridinium iodide; xxvii. Methanesulfonate 1-((2-((E)-1-(2-aminothiazol-4-yl)-2-((1S,8R)-5-(((3-(dimethylcarbamoyl)pyridinium-1- Methanesulfonate 1-((((4-((1E,4Z,6E)-5-hydroxy-7-(4-hydroxy-3-methoxyphenyl)-3-oxohepta-1,4,6-trien-1-yl)- 2-methoxyphenoxy)carbonyl)oxy)methyl)-3-(methyl-carbamoyl)pyridin-1-io;li.3-carbamoyl-1-((((4-((1E,4Z,6E)-5 methanesulfonate -hydroxy-7-(4-hydroxy-3-methoxyphenyl)-3-oxohepta-1,4,6-trien-1-yl)-2-methoxyphenoxy)carbonyl)methyl)pyridin-1-io;Liv.Methanesulfonate 1-((((1-carboxy-2-(3,4-dihydroxyphenyl)ethyl)carbamoyl)oxy)methyl)-3- (dimethylcarbamoyl)pyridin-1-io; lix. 1-((((4 -acetamidophenoxy)carbonyl)oxy)methyl)-3-(dimethylcarbamoyl)pyridin-1-io;lxxiv.3-(dimethylcarbamoyl)-1-((2-(4-isobutylphenyl)propanoyloxy)methyl)pyridinium mesylate;xxx. 1-(((2,6-diisopropylphenoxy)carbonyl)oxy)methyl)-3-(dimethylcarbamoyl)pyridin-1-io iodide; xxxi. 3-carbamoyl-1-((((2,6-diisopropyl -phenoxy)carbonyl)oxy)methyl)pyridin-1-io;1060. 1-(((((2,6-diisopropylphenoxy)carbonyl)oxy)me iodide tyl)-3-(methoxycarbonyl)pyridin-1-io; 1061. 3-Carboxy-1-((((2,6-diisopropylphenoxy)carbonyl)oxy)methyl)pyridin-1-iodide; 1069. 3-((2,6-diisopropylphenoxy)carbonyl)-1-((((2,6-diisopropylphenoxy)carbonyl)oxy)methyl)pyridin-1-io methanesulfonate; 1082. 1-((((2,6-diisopropylphenoxy)carbonyl)oxy)methyl)-3-(methoxycarbonyl)pyridin-1-ium methanesulfonate; and 1083. 3-Carboxy-1-((((2,6-diisopropylphenoxy)carbonyl)oxy)methyl)pyridin-1-io methanesulfonate |
| priorityDate | 2012-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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