abstract |
A first protein molecule comprising a first binding site for binding to a first epitope of a first cell surface molecule, covalently linked to at least one saponin via at least one linking moiety and/or via an oligomeric or polymeric backbone to an amino acid residue of said first protein molecule, or directly covalently bound to an amino acid residue of said first protein molecule, wherein - the first binding site comprises or consists of an immunoglobulin, such as an antibody or an IgG, or comprises or consists of at least one ligand for binding to a cell surface molecule such as EGF or a cytokine, and - wherein the at least one saponin is selected from the group consisting of: SO1861, SA1641, GE1741, QS- 21, QS-21A, QS21-B, Quil-A, SO1832, SO1904 and SO1862. |