abstract |
An anti-PD-L1 (VHH) single domain antibody, comprising a complementary determining region (CDR) consisting of CDR1 as set out IN SEQ ID NO: 5, CDR2 as set out in SEQ ID NO: 6 and CDR3 as set forth in SEQ ID NO: 7, wherein said CDR1, CDR2, and CDR3 are separated by the VHH chain FR1, FR2, FR3, and FR4 framework regions, and the anti-PD-single domain antibody. L1 (VHH) can block the binding between PD-L1 and PD-1. |