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grantDate 2022-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2022-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-2898781-T3
titleOfInvention Systems for the treatment of cardiac dysfunction
abstract System for treating cardiac dysfunction, comprising: a pacing circuit configured to deliver a pacing pulse to at least one cardiac chamber of a patient's heart; and at least one controller (52) configured to execute delivery of a stimulation pattern of pacing pulses to the at least one cardiac chamber, wherein at least one of the pacing pulses has a first pacing pattern configured to reduce at least one of the end systolic volume (ESV) and end diastolic volume (EDV) in the heart and at least one of the pacing pulses has a second pacing pattern different from the first pacing pattern, wherein the controller (52) is arranged to deliver the pacing pattern having the pacing pulses with the first pacing pattern pacing a ventricle 40 to 90 ms after atrial activation, and having the pacing pulses with the second pacing pattern pacing. pacing by pacing the ventricle 100 to 180 ms after atrial activation, to reduce at least one of v end systolic volume (ESV) and end diastolic volume (EDV) by at least 5% and maintain at least one of end systolic volume (ESV) and end diastolic volume (EDV) averaged at such reduced volume during a time period of at least one hour, characterized in that the controller is arranged to deliver the pacing pattern having the pacing pulses with the first pacing pattern and the pacing pulses with the second pacing pattern to have 9 or 10 pulses with the first stimulation setting and 1 or 2 pulses with the second stimulation setting.
priorityDate 2015-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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