http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2898278-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b675ddd8e3e8998414d84517fc019551 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bb8ac194ffb9c67097af35d055777d8a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-444 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-409 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-555 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-275 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-546 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-409 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-555 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 |
| filingDate | 2018-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d51927455533c84dc1df9ac4067a320 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b0eedb35749b9f4b56c11769a2f5d28f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_737e729e387aa23c0e92f9fb728f0410 |
| publicationDate | 2022-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2898278-T3 |
| titleOfInvention | Corroles for the treatment of poxvirus infection |
| abstract | A corrole of type A3 or A2B of formula (I): **(See formula)** where: - Y1 and Y2 are identical or different and each one is chosen independently from -H, -SO3H, -SO3-, - NO2, -CHO, -NH2, -NH3+, -COOH, -COO- - M represents 3H or a metal chosen from the group of Cu, Mn, Fe, Co, V, Cr, Ti, Ag, Rh, Ru, Mo, Zr, Au, Pt, Ir, Re, W, Hf, Li, Al, Ga, Ge, Sn, As, Sb, Pb, Bi, La, Gd, Tb or Th - A1 and A2 are the same or different and each represents a phenyl group of formula (II), **(See formula)** or a pyridinium group of formula (III) **(See formula)** or a five-membered heterocycle of formula (IV) **(See formula)** each being chosen from R1, R2, R3, R4 and R5 of formula (II); each of R1', R2', R4' and R5' of the formula (III); each of R1", R2" and R3" of formula (IV), of: (a). -H, -CN, -NO2, -CHO, -SO3H, -OH, -SH, -C≡CH, -NH2, -COOH, -CONH2, (b) a halogen atom, selected from a chlorine atom, a fluorine atom, a bromine atom or an iodine atom, (c) an alkyl chain (C1 -C8), (d) a PEG chain of the formula -(CH2-CH2-O)nH or of the formula -(CH2-CH2-O)n-CH3, where n is an integer chosen from 1, 2 , 3, 4 or 5, (e).-CX3, where X is a halogen atom selected from a chlorine atom, a fluorine atom, a bromine atom or an iodine atom, (f).-ORa,- NRaRb, -NHRa, -COORa, -CONHRa, -CONRaRb, -SO2Ra, -CORa, -SRa, -C≡CRa, with Ra and Rb being independently chosen from -(CH2-CH2-SO3H), an alkyl chain (C1- C8), a PEG chain of formula -(CH2- CH2-O)nH, or of formula -(CH2-CH2-O)n-CH3, where n is an integer chosen from 1, 2, 3, 4 or 5 (g) a group of the formula **(See formula)** where Rc is -COOH or -SO3H (h) a pyridinium group of the formula **(See formula)** where Rd is a a (C1-C8) alkyl chain, or -(CH2)nSO3-, n being an integer chosen from 1, 2, 3, 4 or 5, - R3' being chosen from formula (III) from - -H, -CONH2, - a (C1-C8) alkyl - a PEG chain of formula -(CH2-CH2-O)nH or of formula -(CH2-CH2-O)n-CH3, where n is a chosen integer of 1, 2, 3, 4 or 5, - a group -(CH2)nSO3-, where n is an integer chosen from 1, 2, 3, 4 or 5 - -ORa, -NRaRb, -NHRa, -COORa, -CONHRa, -CONRaRb, -CORa, Ra and Rb being chosen independently from -(CH2-CH2-SO3H), a (C1-C8) alkyl chain, a PEG chain of formula -(CH2-CH2-O)nH, or of formula -(CH2-CH2-O)n-CH3, where n is an integer chosen from 1, 2, 3, 4 or 5, - E of formula (IV) is chosen from -O-, - S-, -Se-, -NH-, or a pharmaceutically acceptable salt thereof, or an optical isomer thereof, for use in treating a poxvirus infection in human or non-human animals. |
| priorityDate | 2017-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 59.