| abstract |
A pharmaceutical composition comprising granules and having an intragranular and an extragranular phase, said composition comprising: eslicarbazepine acetate in an amount of from 80 to 90% by weight of the total weight of the composition, wherein eslicarbazepine acetate is present in the intragranular phase; povidone in an amount of from 3 to 10% by weight of the total weight of the composition, where the povidone is present in the intragranular phase; croscarmellose sodium in an amount of from 3 to 10% by weight of the total weight of the composition, where 50% of croscarmellose sodium is present in the intragranular phase and 50% is present in the extragranular phase; and magnesium stearate in an amount of from 0.1 to 3% by weight of the total weight of the composition, where the magnesium stearate is present in the extragranular phase, where the composition is in the form of a tablet and is prepared by wet granulation using a granulating liquid wherein the granulating liquid is water. |