| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2308d2f079e23c4a316e143f69b01946 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6886 |
| filingDate |
2015-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2022-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a85ee3cba9ab9562c20c82c3977b8885
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f37a7b16780b13e1d8a542d8ff661088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b700d338a96ce861d65f7c3356dcd5a5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3594102e7538e4de8280735cb781c0fe
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f01ccc2f631c3bf26f5d99afc0c80781
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9adf5c9eafb2a2784680efcbd2d22e25 |
| publicationDate |
2022-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
ES-2896404-T3 |
| titleOfInvention |
Methods for determining responsiveness to MEK/ERK inhibitors |
| abstract |
A method of predicting the responsiveness of a cancer cell to a MEK inhibitor, comprising: detecting the presence of at least one mutation in ADAM12 in the cancer cell by contacting a nucleic acid sample derived from the cancer cell with at least one oligonucleotide that allows the specific detection of the mutation; wherein the presence of mutation in ADAM12 is indicative of a decreased responsiveness of the cancer cell to the MEK inhibitor. |
| priorityDate |
2014-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |