| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_79d99dd0dd21ecb1aaf1659312de6554
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7e6af933919fad4bb75411810e6c3c25 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-575
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-522
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-205
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-015
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39575
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-445 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-015 |
| filingDate |
2012-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2022-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_04f2e18b456ae98eea5ccb1356629e69
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bee218bcfe1269d0aeb5061b84e842fd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_286885f5204bfd7ef03fec72c145d123
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c894554b04a8e1d1c1deab6016f9f377
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_55fcfa2babe90b055a3f849d9af75113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ccfa30e627b363245a693c38afeb0ea5 |
| publicationDate |
2022-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
ES-2894724-T3 |
| titleOfInvention |
Falciparum malaria vaccine |
| abstract |
A vaccine for preventing or reducing the severity of malaria comprising a composition that leads to inhibition of parasite egress from red blood cells or inhibits parasite egress of said red blood cells, wherein said composition comprises a PfSEP-1 polypeptide (Plasmodium falciparum schizont-1 efflux protein) comprising the amino acid sequence of SEQ ID NO: 3 or a fragment thereof or a nucleic acid encoding a PfSEP-1 gene product comprising SEQ ID NO: 3 or a fragment thereof, wherein said fragment is defined by SEQ ID NO: 2 and elicits an immune response that inhibits parasite egress from red blood cells, or wherein said composition comprises a polynucleotide comprising the nucleic acid sequence of SEQ ID NO : 4 or a fragment thereof, wherein said fragment comprises the nucleic acid sequence of SEQ ID NO: 1, and wherein said polynucleotide fragment encodes a PfSEP-1 gene product that causes or an immune response that inhibits the exit of the parasite from the red blood cells, or where said composition comprises a purified antibody or an antigen-binding fragment thereof that specifically binds to a PfSEP-1 antigen of SEQ ID NO: 3 or a fragment thereof, wherein said fragment comprises the amino acid sequence of SEQ ID NO: 2 and wherein said antibody or antigen-binding fragment thereof inhibits parasite egress from red blood cells. |
| priorityDate |
2011-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |