| abstract |
A fusion protein comprising at least two VHHs, comprising a single heavy chain variable domain (VHH) antibody that binds to a biomaterial, selected from the group consisting of hydroxyapatite, calcium phosphate, or a biocompatible metal coated with hydroxyapatite or calcium phosphate, and further comprising at least one VHH that binds to a growth factor BMP, which fusion protein is used in a method of treatment for the regeneration, reconstruction and replacement of lost and worn tissues. |