| abstract |
A compound of formula (I) **(See formula)** characterized in that R is straight or branched chain alkyl having 1 to 6 carbon atoms, where 1 to 5 hydrogen atoms can be replaced by Hal or OH ; W is CH or N; A denotes one of the following groups: **(See formula)** X is N or CR'''; X1, X2 is N or CR'''; X3 is N or CR'''''; Y is O, S, SO or SO2; R', R'' each independently denote H, Hal, or straight or branched chain alkyl having 1 to 12 carbon atoms; R''', R'''' independently denote H, Hal, NR3R4, CHR3R4, OR3, CN, straight or branched chain alkyl having 1 to 12 carbon atoms, wherein 1 to 3 CH2 groups may be replaced by a group selected from O, NR3, S, SO, SO2, CO, COO, OCO, CONR3, NR3CO and wherein 1 to 5 hydrogen atoms may be replaced by Hal, NR3R4 or NO2; R''''' denotes H, Hal, NR3R4, CHR3R4, CN, straight or branched chain alkyl having 1 to 12 carbon atoms, wherein 1 to 3 CH2 groups may be replaced by a group selected from NR3, S , SO, SO2, CO, COO, OCO, CONR3, NR3CO and where 1 to 5 hydrogen atoms can be replaced by Hal, NR3R4 or NO2; R3, R4 each independently denotes H or a straight or branched chain alkyl group having 1 to 12 carbon atoms; Q denotes one of the following groups: **(See formula)** Z1 is S, O, NR3; Z2, Z3 independently denote CR5, CR6 or N; T is N, CH or CR7; R5, R6, R7 independently denote H, Hal, NR3R4, NO2, straight or branched chain alkyl having 1 to 12 carbon atoms, wherein 1 to 3 CH2 groups may be replaced by a group selected from O, NR3, S , SO, SO2, CO, COO, OCO, CONR3, NR3CO and where 1 to 5 hydrogen atoms may be replaced by Hal, NR3R4, NO2, OR3, Het, Ar, Cyc, or denotes Ar, Het or Cyc; R8 denotes H, methyl, or straight or branched chain alkyl having 2 to 12 carbon atoms, wherein 1 to 3 CH2 groups may be replaced by a group selected from O, NR3, S, SO, SO2, CO, COO, OCO, CONR3, NR3CO and where 1 to 5 hydrogen atoms can be replaced by Hal, NR3R4 or NO2; Hal denotes F, Cl, or I; Het denotes an aromatic ring, saturated or unsaturated, being monocyclic or bicyclic or fused bicyclic and having 3 to 8 members and containing 1 to 4 heteroatoms selected from N, O and S, which may be substituted by 1 to 3 substituents selected from R5, Hal and OR3; Ar denotes a 6-membered carbocyclic aromatic ring or bicyclic aromatic unfused or fused ring system, which is optionally substituted by 1 to 3 substituents independently selected from R5, OR3 and Hal; Cyc denotes a saturated carbocyclic ring having from 3 to 8 carbon atoms which is optionally substituted by 1 to 3 substituents independently selected from Ro, Hal or OH; m and n denote independently of one another 0, 1, 2 or 3. and pharmaceutically usable solvates, salts, tautomers, enantiomers, racemates and stereoisomers thereof, including mixtures thereof in all ratios and compounds of formula I, wherein one or more H atoms are replaced by D (deuterium). |