| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0249c8c96ed09a989cb0d43c51a3060d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y403-01005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y403-01024 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-88 |
| filingDate |
2014-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2022-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22804a3e5c7dd170e51e39cd0308213d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_427e95f0b755520bc3cd13d0790d9088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d433a282ef372585d00be4dc404d8e45
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b974f05dd3a60b2e29364f51fac10e39
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3b5e6a6b1b98ff6cd931b3353f25e64 |
| publicationDate |
2022-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
ES-2890955-T3 |
| titleOfInvention |
Ammonia lyase modified phenylalanine polypeptides |
| abstract |
A modified polypeptide having phenylalanine ammonia lyase (PAL) activity comprising: a) an amino acid sequence having at least 85% sequence identity with the reference sequence SEQ ID NO: 4 or a functional fragment thereof same; b) at least one amino acid residue difference compared to SEQ ID NO: 4 or the functional fragment thereof at one or more amino acid positions; and c) showing reduced sensitivity to proteolysis compared to the reference sequence SEQ ID NO: 4, wherein the amino acid residue difference is R305L or R305M when aligned with SEQ ID NO: 4, and wherein the positions of the amino acids are numbered with reference to SEQ ID NO: 4. |
| priorityDate |
2013-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |