abstract |
miRNA-324 molecule, isomiR, or a precursor thereof, or a composition comprising said miRNA-342 molecule, isomiR, or a precursor thereof, for use as a medicament for preventing, treating, reversing, curing and/or or delay head and neck cancer or preneoplastic mucosal change, wherein said miRNA-342 or isomiR molecule comprises the seed sequence identified as SEQ ID NOs: 79-99, 14 and/or 15 and has at least 80%, 85%, 90%, 95%, 97%, 98%, 99%, or 100% identity to SEQ ID NOs: 245-318, 25 and/or 26, wherein said precursor is a nucleic acid that has at least 90% identity to SEQ ID NO: 5 and/or 33 and is at least 50 nucleotides in length. |