abstract |
A compound of Formula (I) or a pharmaceutically acceptable salt thereof: **(See formula)** where X is CH or N; n is 0, 1 or 2; R1 is methyl, ethyl, cyanomethyl, C-linked acetamido, methyl acetate, 2-hydroxyethyl, 2-hydroxy-1-propyl, 1,3-dihydroxy-2-propyl or 1,2-dihydroxy-3-propyl; R2 is independently selected from halo, amino, hydroxymethyl, C1-2 alkyl optionally substituted with up to three fluoro, or C1-2 alkoxy optionally substituted with up to three fluoro; R3 is phenyl, pyridyl, pyrimidinyl, pyrazinyl or pyridazinyl wherein each of these groups may be optionally substituted with one or two substituents selected from halo, cyano, C1-2 alkyl optionally substituted up to three fluoro, and C1-2 alkoxy optionally substituted up to three fluoro, where the substituents may be the same or different; or R3 is cyclohexyl which may be optionally substituted with one or two fluoro or chloro wherein each substituent may be attached to the same carbon atom and each substituent may be the same or different; or R3 is tetrahydropyran; and R4 is H or methyl. |