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filingDate 2009-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_750d74909866e32de2a848138e7c5a17
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publicationDate 2021-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-2884674-T3
titleOfInvention Cancer treatment with the hypoxia-activated prodrug TH-302 in combination with docetaxel or pemetrexed
abstract Compositions for use in a method of treating lung cancer, wherein the first composition comprises (1-methyl-2-nitro-1H-imidazol-5-yl) N,N'-bis(2- bromoethyl) phosphoroidal (TH-302) and the second composition comprises docetaxel, wherein an effective dose of TH-302 is administered first, followed by administration of a therapeutically effective dose of docetaxel 2 to 24 hours after the end of the administration of TH-302.
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