http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2882543-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e0bf0928b608797b70bbc2b91c7e52e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-501 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D237-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D237-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B43-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D237-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 |
| filingDate | 2016-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d3d291cbec7d5d9c6e39f12fd8a5bd4b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1ed4add6cd848b962318e58b1d0fce24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e19d1ef58f6990f08f11054f1a5a978 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_96db6eda41953eb89a8a3b2e5a746261 |
| publicationDate | 2021-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2882543-T3 |
| titleOfInvention | Process for the preparation of 4-amino-pyridazines |
| abstract | A process for the preparation of a pyridazine amino compound of formula V or a salt, tautomer or N-oxide thereof characterized in that it comprises **(See formula)** the reaction step of (a) an amino compound of dichloropyridazine of the formula IVa or a salt, tautomer or N-oxide thereof or (b) an amino compound of dichloropyridazine of the formula IVb or a salt, tautomer or N-oxide thereof or (c) a mixture of (a) and (b) **(See formula)** with hydrogen in the presence of a hydrogenation catalyst, wherein the process further comprises the step of reacting (a) a dichloropyridazine amino compound of formula IVa or a salt , tautomer, or N-oxide thereof or (b) a dichloropyridazine amino compound of the formula IVb or a salt, tautomer, or N-oxide thereof or (c) a mixture of (a) and (b) in a reaction in a single vessel comprising the steps of the reaction of the compound of formula II **(See formula)** with POCl3 and through the reaction of the product of r resulting crude reaction with an amine compound R1-NH2 or a salt thereof, wherein the isolation step of the trichloropyridazine compound of formula III **(See formula)** is omitted and wherein the trichloropyridazine is transferred to a phase organic and used directly in the next reaction step; and where R1 is H, C1-C2-alkyl or C1-C2-alkoxy-C1-C2-alkyl. |
| priorityDate | 2015-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 230.