| abstract |
A combination of (i) an anti-HER-3 antibody comprising a heavy chain amino acid sequence comprising a CDRH1 represented by GGSFSGYYWS, a CDRH2 represented by EINHSGSTNYNPSLKS and a CDRH3 represented by DKWTWYFDL, and an amino acid sequence of the light chain comprising a CDRL1 represented by RSSQSVLYSSSNRNYLA, a CDRL2 represented by WASTRES and a CDRL3 represented by QQYYSTPRT; and (ii) an anti-EGFR antibody, for use in the prevention or treatment of hyperproliferative disease. |