| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_50eb752940fa4aa36756a6bc9f6f3504 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-507
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-75
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-92
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-565 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2827
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-3955
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39558 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-22 |
| filingDate |
2015-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2021-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13fe937301c3f0220669a606a82873a6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f4702b2cf4b338bf36bb897f3923920
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b89e317cba07131e6eb83eb1090ed672
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ce13c7e6469d8949818853d22a05e394
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a6f0114579c5c780f38b2fffae8547b |
| publicationDate |
2021-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
ES-2878091-T3 |
| titleOfInvention |
Human antibodies against PD-L1 |
| abstract |
An isolated antibody or antigen-binding fragment thereof that binds to human programmed death ligand 1 (PD-L1) protein, wherein (a) the isolated antibody or antigen-binding fragment comprises a variable region of the heavy chain (HCVR) with at least 90% identity to SEQ ID NO: 82 and a light chain variable region with at least 90% identity to SEQ ID NO: 90 and / or (b) the antibody or antigen-binding fragment comprises a heavy chain variable region (HCVR) of SEQ ID NO: 82 with 10 or fewer conservative amino acid substitutions and a light chain variable region (LCVR) of SEQ ID NO: 90 with 10 or less conservative amino acid substitutions; wherein the isolated antibody or antigen-binding fragment thereof binds to monomeric PD-L1 at 25 ° C with a KD of less than 100 pM as measured using surface plasmon resonance. |
| priorityDate |
2014-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |