http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2878041-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a693232b92910547c898db10feb83fef |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D265-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-497 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
| filingDate | 2016-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1438617cfe659e3f24443ba62c107a04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_208dba8dc393b27db5ccfae095b8acc7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_57e298f90c80d4d97a5fe9b85adfe831 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c36c412ea8b7d926b219cbe17fa28393 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d620cd3222d4ee3f99ca3b8cbfd4961a |
| publicationDate | 2021-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2878041-T3 |
| titleOfInvention | Piperazine Carbamates and Methods to Prepare and Use Them |
| abstract | A compound of formula (I): **(See formula)** wherein: R1 is halogen, -OR3, -CN, aryl (optionally substituted with one, two or three residues each independently selected from R4), aryloxy (optionally substituted with one, two or three residues each selected independently from R4), heteroaryl (optionally substituted with one, two or three residues each selected independently from R4), heteroaryloxy (optionally substituted with one, two or three residues selected each one independently of R4), heterocycle (optionally substituted with one, two or three residues each independently selected from R4), cycloalkyl (optionally substituted with one, two or three residues each independently selected from R4), optionally substituted C1-6 alkyl , optionally substituted C2-6 alkenyl, optionally substituted C2-6 alkynyl, -NR9R10, -NR8C(O)R9, -NR8SO2R9, -NR8C(O)OR9, -NR8C(O)NR9R10, - C(O)R9, - C(O)OR9, -C(O)NR9R10, -S(O)wR11, or -SH; R2 is -NR5R6; each R3 is independently selected from H, C1-6 alkyl, haloalkyl, and aminoalkyl; each R4 is independently selected from halogen, -OR3, -CN, nitro, optionally substituted C1-6 alkyl, optionally substituted C1-6 alkenyl, optionally substituted C1-6 alkynyl, cycloalkyl, -NR9R10, -NR8C(O)R9, - NR8SO2R9, -NR8C(O)OR9, -NR8C(O)NR9R10, -C(O)R9, -C(O)OR9, -C(O)NR9R10, -S(O)wR11, and -SH; R5 and R6, together with the nitrogen to which they are attached, form an 8-membered bridged heterocyclic ring selected from **(See formula)** in which the 8-membered bridged heterocyclic ring is optionally substituted with one or more substituents independently selected from halogen, -CN, oxo, optionally substituted C1-6 alkyl, optionally substituted aryl, optionally substituted heteroaryl, optionally substituted heterocycle, optionally substituted cycloalkyl, -S(O)wR11, -OR3, -OR7, -C( O)R9, -C(O)OR9, -C(O)NR9R10, -NR9R10, -NR8C(O)R9, -NR8SO2R9, -NR8C(O)OR9, and -NR8C(O)NR9R10; R7 is alkynyl or (alkynyl)alkyl; each R8 is independently selected from H, optionally substituted alkyl, optionally substituted cycloalkyl, optionally substituted aryl, optionally substituted heteroaryl, and optionally substituted heterocycloalkyl; each R9 and R10 is independently selected from H, optionally substituted alkyl, optionally substituted cycloalkyl, optionally substituted aryl, optionally substituted heteroaryl, and optionally substituted heterocycloalkyl; or R9 and R10, together with the nitrogen to which they are attached, form an optionally substituted heterocycle optionally containing an additional O, N or S; each R11 is independently selected from optionally substituted alkyl, optionally substituted cycloalkyl, optionally substituted aryl, optionally substituted heteroaryl, and optionally substituted heterocycloalkyl; and w is 0, 1 or 2; or one of its solvates, hydrates, tautomers, N-oxides, stereoisomers, or pharmaceutically acceptable salts. |
| priorityDate | 2015-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 121.