| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d4a11679d3a91d63060848f361d2873c |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-71 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-71
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57484
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5011 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6886 |
| filingDate |
2015-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2021-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a9c081e55ffc5eca17b91ebce142471b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_43846d3dba70f0560d7087b941700f75
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9bf3b277baf90081855f122519df8b7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62102673791449294de1cce4c7e7a643
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_58d6cedac5918b946853126e21560a36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06c1af38c90f0f2ca25350925b2a271c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f12f4a648764bda3e28315a189f747a |
| publicationDate |
2021-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
ES-2876232-T3 |
| titleOfInvention |
Biomarker to predict sensitivity to and use of protein kinase inhibitor |
| abstract |
A method for predicting the sensitivity of a subject cancer patient to a c-MET protein kinase inhibitor comprising: (a) measuring the expression level of a Recepteur d'Origine Nantais (RON) in an active form comprising a splice variant or mutant of the RON gene within a biological sample that is obtained from a subject by a detection method using an agent selected from an antisense oligonucleotide, a primer pair, or a binding probe specifically to active RON mRNA or an antibody, peptide, or nucleotide that specifically binds to active RON protein; and (b) determining the subject's sensitivity to a protein kinase inhibitor based on the result that was measured in step (a). |
| priorityDate |
2014-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |