Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_82ae8798cdec6cc8f8ad3eb62813831e |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-343 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-321 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088 |
filingDate |
2011-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2021-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_701d1a5c4fabca996add034159cec0a0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_32688133056c9c8fb5d43dceb323b600 |
publicationDate |
2021-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
ES-2873893-T3 |
titleOfInvention |
Methods and compositions for the specific inhibition of beta-catenin by double-stranded RNA |
abstract |
An isolated double-stranded ribonucleic acid (dsRNA) comprising first and second nucleic acid strands, wherein each of the first and second nucleic acid strands is at least 25 nucleotides in length, wherein the first and second second nucleic acid strands form a duplex region. of at least 25 base pairs, and wherein said second strand of the dsRNA is complementary to at least 22 nucleotides of a target β-catenin sequence, the target β-catenin sequence being SEQ ID NO: 2395, so that dsRNA reduces the expression of the β-catenin target gene when introduced into a mammalian cell. |
priorityDate |
2010-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |