http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2870679-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7df267c0e21d6b0ad2a3490807c38477 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-04 |
| filingDate | 2016-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64cfe2827063b7f625781055d7470261 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26d6a2a351e8806f9a594d2f6869b441 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8feccfe08dc2517c9ea22925fd6a746 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17c2d651d72dc609b2e8c486302adbd1 |
| publicationDate | 2021-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2870679-T3 |
| titleOfInvention | Pyrimidine compound |
| abstract | A compound of formula (1) or a pharmaceutically acceptable salt thereof: ** (See formula) ** where X is methylene, an oxygen atom, a sulfur atom, SO, SO2 or NR7 where R7 is a carbon atom hydrogen or an alkyl group of 1 to 3 carbon atoms; R1 and R2 are independently a hydrogen atom or a substituted or unsubstituted alkyl group of 1 to 6 carbon atoms, provided that when the alkyl group is substituted, it is substituted with 1 to 4 equal or different substituents selected from the group consisting of a hydroxy group, a halogen atom and an alkoxy group of 1 to 6 carbon atoms; R3 is an alkyl group of 1 to 6 carbon atoms, an alkoxy group of 1 to 6 carbon atoms or an alkylthio group of 1 to 6 carbon atoms; R4 is a hydrogen atom, a halogen atom, a hydroxy group, an alkyl group of 1 to 6 carbon atoms, an alkoxy group of 1 to 6 carbon atoms, or a cyano group; Y1 is a single bond, - (CR9R10) p-, -CH = CH- (CR9R10) q-, -C≡C- (CR9R10) q- or - (CR9R10) rO- (CR9'R10 ') r'- where R9, R10, R9 'and R10' are independently a hydrogen atom or an alkyl group of 1 to 4 carbon atoms; Y2 is a single bond or -C (O) -; L is a substituted or unsubstituted straight chain alkylene of 2 to 6 carbon atoms or a divalent group obtained from a 4 to 8 membered cycloalkane, provided that when the straight chain alkylene or cycloalkane is substituted , is substituted with 1 to 4 equal or different substituents selected from the group consisting of an alkyl group of 1 to 5 carbon atoms, a hydroxy group and a halogen atom, and any of the methylene group in the straight chain alkylene of L is optionally replaced with a carbonyl group; Ry R6 are independently a hydrogen atom or a substituted or unsubstituted alkyl group of 1 to 6 carbon atoms, or Ro R6 are attached to any carbon atom of L to form a saturated 4- to 8-membered nitrogen-containing heterocycle , or Ry R6 are taken together to form a saturated 5- to 8-membered nitrogen-containing heterocycle, substituted or unsubstituted; provided that when the alkyl group is substituted, it is substituted with 1 to 4 the same or different substituents selected from the group consisting of a hydroxy group and a halogen atom; when the saturated 4- to 8-membered nitrogen-containing heterocycle or the saturated 5- to 8-membered nitrogen-containing heterocycle is substituted, it is substituted with 1 to 4 the same or different substituents selected from the group consisting of a methyl group, a group ethyl, a propyl group, a hydroxymethyl group, a hydroxyethyl group, a carbonyl group, a hydroxy group, and a halogen atom; m is 0 or 1; p is an integer from 1 to 6; q and q 'are independently an integer from 0 to 4; r is an integer from 0 to 5, and r 'is an integer from 1 to 5, provided that r' is an integer of 2 or more when the sum of r and r 'is 5 or less and Y2 is a single link; y is independently a single bond or a double bond. |
| priorityDate | 2015-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 249.