http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-286931-A1

Outgoing Links

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3351f64b28e5ef2ef8b0da719c4e8ea8
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-155
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-185
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D-
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-185
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-155
filingDate 1963-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1963-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-286931-A1
titleOfInvention PROCEDURE FOR THE PREPARATION OF NEW DERIVATIVES OF SALICYLIC ACID
abstract Process for the preparation of new salicylic acid derivatives of the general formula: ** (See formula) ** wherein: a) R represents a substituent selected from the group consisting of: -a hydrogen atom, a group such as formyl, acetyl, carbethoxy and carbobenzoxy -COO-CH2-C6H5, a phenyl nucleus, a phenyl nucleus substituted by a halogen atom, a trifluoromethyl radical, a lower alkyl radical of up to 5 atoms of carbon, a lower alkoxy radical of up to 5 carbon atoms, a methylene dioxy group, a nitro group and an amino group, b) R 'represents a hydrogen atom, an acetyl group, a lower alkyl radical of up to 5 carbon atoms, carbon, a lower alkyl radical of up to 5 carbon atoms, c) Y represents a hydrogen atom, a hydroxyl radical OH and a methyl radical -CH3, d) X represents a hydroxyl radical OH, an inner alkoxy group of up to 5 atoms carbon, as well as their addition salts, characterized in that a derivative of the formula is condensed: ** (See formula) ** in which; a) Z represents a chlorine or bromine atom, b) R ', Y and X have the same meanings as above, on a N-monosubstituted piperazine of the formula: ** (See formula) ** wherein R has the same meanings as above, the reaction being carried out in a solvent such as an aromatic carbide, and a low molecular weight alcohol, at the boiling temperature of the chosen solvent (60º to 135º) and in the presence of an alkaline hydrazide acceptor agent, such as K2CO3 or triethylamine, or an excess of the N-monosubstituted piperazine. (Machine-translation by Google Translate, not legally binding)
priorityDate 1962-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 39.