http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2865334-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0fcbc9ca53bc68f405f71764197469b5 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-695 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-567 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-74 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-567 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4745 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D217-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-575 |
| filingDate | 2016-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0c5cc2230d913de91183234b346ed15 |
| publicationDate | 2021-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2865334-T3 |
| titleOfInvention | Differential diagnosis method of ACTH-dependent Cushing syndrome |
| abstract | A differential diagnosis method of adrenocorticotropic hormone (ACTH) -dependent Cushing's syndrome in a patient where the differential diagnosis is made between ectopic ACTH syndrome and Cushing's disease, the method comprising the steps of: (i) obtaining from a patient an ACTH concentration in a fluid sample obtained from the left or right inferior petrosal venous sinus and an ACTH concentration from a fluid obtained from a peripheral venous sample, and (ii) obtain an ACTH concentration ratio from ACTH levels, where the patient is a patient with Cushing's syndrome and elevated ACTH levels also given a dose of glucocorticoid receptor antagonist (GRA) sufficient to increase pituitary gland ACTH by at least two times in persons with normal hypothalamic-pituitary-adrenal (HPA) function, where samples were obtained at least two hours after l Administration of GRA, where an ACTH concentration ratio greater than 3 to the ACTH concentration of the inferior venous sinus sample over the peripheral venous sinus sample serves as a diagnosis of Cushing's disease. |
| priorityDate | 2015-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 266.