Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eec40d1e34ae619a1a28c526b18c6174 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-95 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1241 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y207-0705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62 |
filingDate |
2016-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2021-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b9e0695144ca7567391bfa4eb7328d58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dcb4b7d6b5be3e1b563811d0c7c8c92c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_074c78aea781f35267a39ec0b5c17337 |
publicationDate |
2021-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
ES-2862412-T3 |
titleOfInvention |
Modification of RNA-related enzymes for improved production |
abstract |
A method of producing a protected mRNA oligonucleotide or mRNA analog, wherein a heterodimer comprising a fusion protein facilitates the steps of transferring and methylating a guanylyl molecule to the 'end of the mRNA oligonucleotide or mRNA analog, wherein the fusion protein comprises a guanylyl transferase. and a small molecule ubiquitin-like protein (SUMO), wherein the fusion protein has an amino acid sequence at least 90% identical to SEQ ID NO: 1 and SEQ ID NO: 6. |
priorityDate |
2015-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |