abstract |
Crystalline form of Sofosbuvir designated Form E and characterized by data selected from one or more of the following: an X-ray powder diffraction pattern having peaks at: 12.4, 16.2, 17.2, 25.0, and 25.3 degrees two theta ± 0.1 degrees two theta; an X-ray powder diffraction pattern as illustrated in Figure 1 or Figure 7; an X-ray powder diffraction pattern having peaks at: 12.4, 16.2, 17.2, 25.0 and 25.3 degrees two theta ± 0.1 degrees two theta and no peaks at: 10 , 9 and 14.2 degrees two theta ± 0.2 degrees two theta, and combinations of these data. |