abstract |
Use of a wetting agent in a suspension aerosol formulation comprising particles of formoterol fumarate dihydrate and fluticasone propionate suspended in the HFA propellant contained in a metered dose inhaler comprising a container and a metering valve, to reduce the deposition of particles in the surfaces of the container and the metering valve, wherein the wetting agent is selected from the group consisting of ethanol, propylene glycol, glycerol, butanediol, and mixtures thereof, preferably wherein the wetting agent is ethanol. |