http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2859157-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_79316eeaf1bb028331ec423337beb09a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_066af93d226b9a8b1151cb1bc45bd190 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D9-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D9-0004 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D235-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 |
| filingDate | 2017-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9094a261e182c36229263d2b063953dc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_537b2da06263323f2d499a5b57b67031 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_69cd9a74bb10647b9271e17486486310 |
| publicationDate | 2021-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2859157-T3 |
| titleOfInvention | Preparation Process for High Purity Dabigatran Etexilate |
| abstract | A process for the preparation of high purity dabigatran etexilate comprising: a) adding a crude product of dabigatran etexilate in water, suspension at 5-30 ° C, and filtering after suspending for 1-2 h to obtain a crude product B ; b) Add the crude product B in acetone, heat to 20-50 ° C to obtain a clear solution, then add water dropwise to the solution, cool the solution to 0-10 ° C and filter to obtain a crude product C ; and c) add crude product C to a mixture of tetrahydrofuran and ethyl acetate, heat to 50-70 ° C to dissolve and then cool to 40-45 ° C, preferably add a seed crystal, slowly cool to 0-5 ° C , then filter, dry the filter cake at 40-50 ° C under vacuum to obtain the high purity dabigatran etexilate. |
| priorityDate | 2016-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.