http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2856899-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_872dd7cd609eb2a937dcfd303d521798 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3e035457406455ea05989c01cb90c8f1 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-553 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5377 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P33-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-553 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P33-02 |
| filingDate | 2016-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0106ac9c5ad8b5836dded49ab81a0c9b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_232eeb5cad4ec7abd9ba2c3b6b459354 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f09612792b56157dff151dd97c5903f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3209ce42218bd9d619013a7369eb6014 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d71b0c0dee5fb331d4af4631f8f97f6d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5968aaac45ca8ae8509815cb50fd48f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9fad83fbb69e36fcfe05dc275f25da7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77880656f4ad230563843bd322ac5b6f |
| publicationDate | 2021-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2856899-T3 |
| titleOfInvention | Compounds |
| abstract | A compound of formula (I), or a salt thereof, ** (See formula) ** (I) where A1 is CH; A2 is selected from CR13 and N; R1 is selected from C1-C6 alkyl, C3-C7 cycloalkyl, C4-C7 heterocycloalkyl, phenyl, C5-C6 heteroaryl, C1-C6 alkoxy, -O- (C3-C7 cycloalkyl) and NR10aR10b; wherein C3-C7 cycloalkyl, C4-C7 heterocycloalkyl, phenyl, C5-C6 heteroaryl, and -O- (C3-C7 cycloalkyl) are optionally substituted with 1 to 3 groups independently selected from hydroxy, methoxy, C1-C3 alkyl, and halogen ; L1 is a linking group selected from -C (O) - and -S (O) n-, where n represents 1 to 2; R3 is selected from hydrogen, halogen, methyl, methoxy, and cyano; R4 is selected from hydrogen, halogen, methyl, methoxy, and cyano; R2 is selected from hydrogen, halogen, Ar, Cy, X, NR5aR5b, and -C (O) -R15; Ar is selected from phenyl and C5-C6 heteroaryl, each of which is optionally substituted with 1 to 3 groups independently selected from halogen and -L2-R7; L2 is a linking group selected from a bond, - (CH2) m-, -O (CH2) m-, -C2-C4- alkenyl-, -O- (C2-C4 alkynyl) -, - (CH2) p-NH - (CH2) q-, and - (CH2) pC (O) - (CH2) q-; wherein m represents 1 to 4 and p and q independently represent 0 to 4; R7 is selected from hydrogen; hydroxy; NR8aR8b; C4-C7 heterocycloalkyl optionally substituted with one or two C1-C3 alkyl groups; C3-C7 cycloalkyl; C1-C6 alkoxy optionally substituted with a group NR14aR14b; and phenyl optionally substituted with 1 to 3 groups independently selected from halogen, methoxy, and methyl; Cy is selected from C3-C7 cycloalkyl, C4-C7 heterocycloalkyl, C5-C7 cycloalkenyl, and C5-C7 heterocycloalkenyl, each of which is optionally substituted with 1 to 3 groups independently selected from C1-C3 alkyl, C1-C3 alkoxy, C4-C7 heterocycloalkyl, NR11aR11b, = O, -C (O) -R15 and -C (O) O-R15; X is selected from C1-C6 alkyl, C2-C6 alkenyl, and C1-C6 alkoxy, each of which is optionally substituted with 1 to 3 groups independently selected from hydroxy, methoxy, halogen, NR13aR13b, and C4-C7 heterocycloalkyl, wherein C4-C7 heterocycloalkyl is optionally substituted with 1 to 3 C1-C3 alkyl groups; R5a is selected from hydrogen; C1-C6 alkyl optionally substituted with a group selected from Ar and Cy; - C (O) -R9; -C (O) -OR9; and -SO2-R9; R5b is selected from hydrogen and C1-C3 alkyl; R8a and R8b are independently selected from hydrogen and C1-C3 alkyl; R9 is selected from C1-C6 alkyl, C3-C7 cycloalkyl, C4-C7 heterocycloalkyl, phenyl, and C5-C6 heteroaryl; R10a and R10b are independently selected from hydrogen and C1-C3 alkyl; R11a and R11b are independently selected from hydrogen and C1-C3 alkyl; R12 is selected from hydrogen, halogen, and methyl; R13 is selected from hydrogen, C1-C3 alkyl, -C (O) - (C4-C7 heterocycloalkyl), -C (O) - (C1-C3 alkyl) and -C (O) - (C3-C7 cycloalkyl); R13a and R13b are independently selected from hydrogen and C1-C3 alkyl; R14a and R14b are independently selected from hydrogen and C1-C3 alkyl; and R15 is selected from C1-C6 alkyl, Ar, C3-C7 cycloalkyl, and C4-C7 heterocycloalkyl. |
| priorityDate | 2015-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.