| abstract |
A pharmaceutical composition comprising a compound having the following Formula (I): ** (See formula) ** or a stereoisomer or a pharmaceutically acceptable salt thereof, and one or more additional therapeutic agents selected from the group consisting of GS- 9131 and GS-9148, wherein: Y1 and Y2 are each, independently, hydrogen, C1-3 alkyl or C1-3 haloalkyl; R1 is phenyl substituted with one to three halogens; X is -CHR2-; W is a bond or -CHR3-; Z is a bond or -CHR4-; R2, R3 and R4 are each, independently, hydrogen or C1-3alkyl; R5 is hydrogen, C1-3alkyl or C1-3haloalkyl; L is -C (Ra) 2-, -C (Ra) 2C (Ra) 2- or -C (Ra) 2C (Ra) 2C (Ra) 2-; and each Ra is, independently, hydrogen, halo, hydroxyl, or C1-4alkyl. |