| abstract |
A compound of formula II ** (See formula) ** wherein R1 is NH C1-C6 alkyl; R2 is C3-C6 cycloalkyl or C1-C6 alkyl; R4 is ** (See formula) ** R5 is H, C1-C4 alkyl, C1-C4 alkoxy, -COOH or -CONR6R7; R6 is H or C1-C4 alkyl; R7 is H, C1-C4 alkyl, C6-C8 aryl, C1-C4 hydroxyalkyl- or heterocyclyl substituted with 0-2 R8; or R6 and R7 are taken together with the nitrogen atom to form a 4-8 membered heterocyclyl group substituted with 0-2 R8 R8 is H, C1-C4 alkyl, halo or OH; or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof. |