| abstract |
Follicle-stimulating hormone (FSH) ligand that enhances the bioactivity of FSH, luteinizing hormone (LH) and chorionic gonadotropin (CG), characterized in that said ligand is an antibody or a fragment thereof and because: heavy chain variable domain contains the following CDRs: - VH-CDR1, defined by the sequence GFTFSSSY (SEQ ID NO: 5); - VH-CDR2, defined by the sequence IYAGTGGT (SEQ ID NO: 6); - VH-CDR3, defined by the sequence ARHGSYFDY (SEQ ID NO: 7); and the variable domain of the light chain contains the following CDRs: - VL-CDR1, defined by the sequence QSVDYDGDSY (SEQ ID NO: 8); - VL-CDR2, defined by the sequence AAS; - VL-CDR3, defined by the sequence QQSNEDPYT (SEQ ID NO: 9). |