| abstract |
A composition for use in the prevention or treatment of hyperlipidemia, fatty liver disease or arteriosclerosis, comprising an oxynomodulin derivative conjugate as an active ingredient, wherein the oxynomodulin derivative conjugate comprises: an oxytomodulin derivative comprising the amino acid sequence of SEQ ID NO: 24, 25 or 26; an immunoglobulin Fc region; and a non-peptidyl polymer, wherein the non-peptidyl polymer joins the oxyntomodulin derivative and the immunoglobulin Fc region. |