abstract |
A composition comprising retinol and a therapeutically effective amount of a dipeptide derivative of formula (I): R1 -AAB-AAC-R2 Formula (I) or an isomer, or a salt thereof, and optionally a pharmaceutically or cosmetically acceptable carrier , wherein R1 is an acyl radical having up to 19 carbon atoms; AAB is Tyr and AAC is Tyr, or AAB is Val and AAC is Ala; R2 is OR3, NHR4 or NHNHR5; R3 is H, an alkyl, aralkyl or aryl radical having up to 19 carbon atoms; R4 or R5 is independently H, OH, an alkyl, aralkyl, aryl radical having up to 19 carbon atoms. |