| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d6b27c5e46623db382f82549bf4e8a88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c69def3bf2d75c80ac422fcf66bf0e48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_efe5cb41776eb78d2dd159fe0456824f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9d54375a5a792faa4bc04f77489921c1 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2330-51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-531
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16043
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1132
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1138
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-867
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-82
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
| filingDate |
2016-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2021-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_abfaaa23d922978b091e821a322d4284
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_744692806fdb738a74de71bc3d0338bb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8cd0dddc6de3828ba4240481b8ac453c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd4ceaec33f0f2d6d15374f3d99c5dc3 |
| publicationDate |
2021-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
ES-2833449-T3 |
| titleOfInvention |
Gene therapy for the treatment of HIV and its uses |
| abstract |
An expression vector comprising (a) at least one nucleic acid sequence encoding a transcriptional gene silencing element; and (b) at least two other nucleic acid sequences selected from the group consisting of a nucleic acid sequence encoding a nucleic acid molecule that inhibits an HIV coreceptor; a nucleic acid sequence encoding an HIV fusion inhibitory protein; a nucleic acid sequence encoding an inhibitor of HIV replication; and a nucleic acid sequence encoding a virus entry inhibitor; wherein the at least one nucleic acid sequence encoding a transcriptional gene silencing element is selected from the group consisting of (i) a silencing nucleic acid targeting a sequence from about position 143 to about position 161 of a 5 HIV-1 'LTR, (ii) a silencing nucleic acid targeting a sequence from about position 136 to about position 154 of the HIV-1 5'LTR, (iii) a silencing nucleic acid targeting is a sequence from about position 205 to about position 223 of the HIV-1 5'LTR; and (iv) a silencing nucleic acid targeting a sequence from about position 350 to about position 368 of the HIV-1 5'LTR. |
| priorityDate |
2015-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |