Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_23e985a18173b95d89acbfff1cdb2ec0 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-385 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-4846 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0021 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-48 |
filingDate |
2017-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2021-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e78e69caf327558c0c41e6d1bd35961c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e4be05339bbf6d31eab846a59753b99 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6836df6164f4268f471b160ec6476f2b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21529ad3e0e380d46e4c362547aeac96 |
publicationDate |
2021-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
ES-2832648-T3 |
titleOfInvention |
Subcutaneous Administration of Long-Acting Factor IX in Humans |
abstract |
A fusion protein comprising a) human factor IX (FIX), and b) human albumin for use in a bleeding prevention procedure in a human patient in a prophylactic dosing regimen, wherein the human FIX is capped N-terminal of human albumin through a peptide linker cleavable by proteases involved in coagulation or is activated by coagulation enzymes, and in which the fusion protein must be administered subcutaneously to the subject at a dose of approximately 10- 50 IU / kg, using a dosage range from about once a day to about once a week. |
priorityDate |
2016-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |