http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2831019-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d5976ba69a401cf70e6f8d1978e47a82 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-137 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-56 |
| filingDate | 2011-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_24fda4f9d6d9f3f7e672a1c425cb7d17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3fb6611f5125015fa45273785307fa2c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c08e36e87ff4c6e990dc60051b9ddb3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5330ac6f5b0e0443b30c84b89a8cbc9a |
| publicationDate | 2021-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2831019-T3 |
| titleOfInvention | A procedure for the processing of active pharmaceutical ingredient particles |
| abstract | A process for reducing the particle size of an active pharmaceutical ingredient prone to polymorphic transformation (API) while maintaining its polymorphic form, which process comprises the step of processing the API by cavitation at a pressure in the range of 300 to 3500 bar , in which the API is suspended at a concentration between 2 and 60% w / v in a solvent in which it is insoluble, in which the process is carried out in the API in the absence of excipients other than the suspension solvent, and in that the resulting particle size distribution of the API particles in the resulting micronized powder comprises a amplitude ((Dv90-Dv10) / Dv50) of less than 2.5. |
| priorityDate | 2010-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 72.