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filingDate 2016-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f95c68b7b05725500a4d9597bc25c34a
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publicationDate 2021-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-2827527-T3
titleOfInvention Manufacture and purification of isoidides
abstract -A method for preparing a composition with increased isoidide content, comprising at least partially separating ionic species from an epimerization product comprising isoidide to obtain an at least partially deionized isoidide composition comprising isoidide and other isohexides; and chromatographically separating the isoidide from the other isohexides to obtain a stream with increased isoidide content and a stream with increased content of the other isohexides, in which the chromatographic separation is carried out by contacting the at least partially deionized isoidide composition. with a resin comprising a strong acid ion exchange resin in the form of calcium 2+; contacting the at least partially deionized isoidide composition comprising isoidide and other isohexides and the resin with a solvent; and eluting a stream with increased isoidide content and a second stream with increased content of the other isohexides.
priorityDate 2015-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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