http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2824554-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_93707860b3c9d99525e6864af10408e2 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0636 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-52 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-564 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56966 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-502 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-505 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-564 |
| filingDate | 2016-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f4615a89b848e72901235e9bd03f71a |
| publicationDate | 2021-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2824554-T3 |
| titleOfInvention | T cell reactivity platform |
| abstract | An in vitro method for testing antigen-specific T cell activation, comprising the steps of: a. Disposing of a phagocytable particle, having a candidate antigen polypeptide intimately associated therewith, wherein the particle with the associated polypeptide has been subjected to a denaturation wash that results in a low enough endotoxin level not to interfere with subsequent steps; b. Arrange a viable antigen presenting cell; c. Contacting the washed particle with the antigen-presenting cell in vitro under conditions that allow phagocytosis of the particle by the antigen-presenting cell; d. Arranging a sample of T cells to be tested comprising viable T cells; and. Contacting the T-cell sample with the antigen-presenting cell that has contacted the particle in vitro under conditions that allow specific activation of T-cells in response to an antigen presented by an antigen-presenting cell; and f. Determine the degree of T cell activation in the T cell sample. |
| priorityDate | 2015-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 678.