http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2824162-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6f41a868f49ca4f32d18d861e3afb411 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-347 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0393 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-18 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0275 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate | 2016-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c12a519fc5861ab9ec63d319fe5e8948 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b58f938442eb1b73ac85e5516d08de3a |
| publicationDate | 2021-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2824162-T3 |
| titleOfInvention | Mammalian Dickkopf 3 (dkk3) as a urinary marker of renal interstitial fibrosis / tubular atrophy (if / ta) and progressive renal failure |
| abstract | An in vitro method to indicate the presence of renal interstitial fibrosis and tubular atrophy (IF / TA), comprising the steps of a) detecting the amount of Dickkopf 3 protein (Dkk3) and / or adducts thereof in a urine sample obtained from a mammalian patient to be diagnosed, and b) reach a conclusion on the extent of renal IF / TA of said patient, where a greater amount of Dkk3 protein and / or adducts of the same in said sample compared to the amount detected in a urine sample from a healthy patient is indicative of higher grade renal IF / TA, and wherein said detection comprises the use of a monoclonal antibody or fragment thereof, wherein said monoclonal antibody is the one produced by huDkk3 -16.1, huDkk3-2.13 or huDkk3-24.20, hybridoma cell lines, deposited under the Budapest Treaty on September 8, 2015 at DSMZ in Braunschweig, Germany under the deposit number DSM ACC3274, DSM ACC3275 and DSM ACC3276, respectively nte. |
| priorityDate | 2015-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 47.