abstract |
Compound of formula (I): ** (See formula) ** wherein ** (See formula) ** Ar is Ra is halogen or haloalkyl; Rb is O- (C2-C4 alkyl), O- (C3-C5 cycloalkyl), N (R10) - (C1-C4 alkyl) or N (R10) - (C3-C5 cycloalkyl); Rc is H; Rd is O- (C2-C4 alkyl) -N (R10) 2, - (C1-C4 alkyl) -R3, O- (C1-C4 alkyl) -R3 or - (C1-C4 alkyl) -N (R10) two; W and Z are each CH; X is -CON (R10) -; Y is CR2; R2 is halogen or haloalkyl; R3 is C3-C8 cycloalkyl-amino, morpolinyl, thiomorpholinyl, or N-alkylpiperazinyl; and R10 is independently H or - (C1-C2 alkyl), n is an integer from 1-3, ** (See formula) ** provided the compound is not ** (See formula) ** |