http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2812883-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf32b60391b469c41e86c353437f5751 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56966 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56972 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6841 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6841 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 |
| filingDate | 2016-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5435f43f2028e8fd3d120e725feab89e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8cfab5d21e4d73b2c6f027feda186f0f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3965bfaab8b567cfd1079dedc3b99ce0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f52b2dd64ac06a1a017167844440903 |
| publicationDate | 2021-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2812883-T3 |
| titleOfInvention | Method of deduction of a biomarker positivity value in percent for selected cells present in a field of view |
| abstract | Method of deducing a value for the% biomarker positivity (PBP) for all cells or, optionally, one or more subsets of them present in a field of view, comprising: (i) generating an image of the former fluorescent signals representative of the nuclei of all cells present in a field of view, and dilating the first fluorescent signals to the diameter of a whole cell to build a first mask of all cells present in the field of view; (ii) constructing a second mask of the second fluorescent signals representative of all areas present in the field of view, expressing a subset biomarker; (iii) optionally, constructing a third mask of the third fluorescent signals representative of all areas present in the field of view, expressing a first biomarker of interest; (iv) combining said first and second masks so as to provide a fourth mask comprising representative fluorescent signals from all cells in the field of view, also expressing the subset biomarker; (v) optionally combining said first and third masks so as to provide a fifth mask comprising fluorescent signals representative of all cells in the field of view, also expressing the first biomarker of interest; (vi) derive a PBP value for all cells expressing the subset biomarker by dividing the total area of the fourth mask by the total area of the first mask; (vii) optionally combining said fourth and fifth masks so as to provide a sixth mask comprising representative fluorescent signals from all cells in the field of view, which (a) express the subset biomarker and the first biomarker of interest ; or (b) express the subset biomarker in the absence of the first biomarker of interest; and (viii) optionally, deducing a PBP value for the first subset of all cells that either (a) express the subset biomarker and the first biomarker of interest or (b) express the subset biomarker in the absence of the first biomarker of interest, dividing the total area of the sixth mask by the total area of the fourth mask. |
| priorityDate | 2015-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 188.