abstract |
Compound of formula (I) or salt thereof: **(See formula)** (in the formula, R1 is H or lower alkyl, R2 is H or CN, any one of G1, G2 and G3 is O, and the two others of G1, G2, and G3 are CH2, ring A is nitrogen-containing aryl or heteroaryl, ring B is cyclic amino, R3 and R4 are the same or different from each other, and are H, halogen, lower alkyl, -alkylene lower-OH, halo-lower alkyl, -O-lower alkyl, -O-halo-lower alkyl, cycloalkyl, CN, OH, -N(lower alkyl)2 or -C(=O)NH2, R5, R6, R7 and R8 are the same or different from each other, and are H, halogen, lower alkyl, halo-lower alkyl, -O-lower alkyl, or CN, or in the case where R5 and R6 are attached to the same carbon atom, R5 and R6 can form cycloalkane or cyclic ether together with carbon atom, and can form spiro ring together with ring B, or ring B can form 6,7-dihydro[1,3]oxazolo[4,5-c] pyridin-5(4H)-yl together with R5 and R6). |