| abstract |
A hydrogel comprising a first polymer and a second polymer, in which the first polymer and the second polymer are the same polymer, and in which the first polymer is connected to the second polymer by linkers of formula (A): ** (See formula) ** where the bond --- is a single or double bond; R1 is -C0-C6 alkyl-NH-, -C0-C6-O- alkyl or -C0-C3-C (O) - alkyl; R2 is a bond, aryl or heteroaryl, where aryl and heteroaryl are optionally substituted with halogen, hydroxy, C1-C6 alkyl, C1-C6 alkoxy, (C1-C6 alkyl) amino or di (C1-C6 alkyl) amino ; R3 is -C0-C6 alkyl-NH-, -C0-C6-O- alkyl or -C0-C3-alkyl-C (O) -; and R4 is hydrogen, C1-C6 alkyl, aryl, or heteroaryl, wherein aryl and heteroaryl are optionally substituted with halogen, hydroxy, C1-C6 alkyl, C1-C6 alkoxy, (C1-C6 alkyl) amino, or di (alkyl). C1-C6) amino. |