abstract |
A composite material comprising: (i) at least one porous, permeable or absorbent secondary component, and at least one biofabricated material comprising a network of non-human collagen fibrils, wherein less than 10% by weight of the collagen fibrils in the material they are in the form of collagen fibers having a diameter of 5 µm or more, in the form of fibrils aligned for 100 µm or more of their lengths, or both; wherein the collagen fibrils do not assemble into fiber bundles; wherein said material does not contain more than 40% by weight of water; and wherein said material contains at least 1% of a lubricant; or (ii) at least one porous, permeable or absorbent secondary component, and at least one biofabricated material comprising a network of recombinant non-human collagen fibrils, wherein the collagen contains substantially no 3-hydroxyproline and, optionally, is substantially free of hydroxylysine. ; wherein said material does not contain more than 25% by weight of water; and wherein said material contains at least 1% of a lubricant; or (iii) at least one layer of a secondary component, and at least one layer of a biofabricated material comprising a network of non-human collagen fibrils, wherein less than 10% by weight of the collagen fibrils in the material are in the form of collagen fibers having a diameter of 5 µm or more, in the form of fibrils aligned for 100 µm or more of their lengths, or both; wherein the collagen fibrils do not assemble into fiber bundles; wherein said material does not contain more than 40% by weight of water; wherein said material contains at least 1% of a lubricant; (iv) at least one layer of a secondary component, and at least one biofabricated material comprising a network of recombinant non-human collagen fibrils, wherein the collagen does not contain substantially 3-hydroxyproline, and optionally, does not contain substantially hydroxylysine; wherein said material does not contain more than 25% by weight of water; and wherein said material contains at least 1% of a lubricant; or (v) at least one layer of a secondary component, and at least two outer layers of at least one biofabricated material having an upper and lower surface, or an inner and outer surface, comprising a network of non-human collagen fibrils , wherein less than 10% by weight of the collagen fibrils in the material are in the form of collagen fibrils having a diameter of 5 μm or more, in the form of aligned fibrils for 100 μm or more of their lengths, or both ; wherein the collagen fibrils are not assembled into fiber bundles, wherein said material does not contain more than 40% by weight of water; and wherein said material contains at least 1% of a lubricant; or (vi) at least one layer of a secondary component and at least two outer layers of at least one biofabricated material having an upper and lower surface, or an inner and outer surface comprising a network of recombinant non-human collagen fibrils, wherein the collagen does not contain substantially 3-hydroxyproline; and optionally contains substantially no hydroxylysine; wherein said material does not contain more than 25% by weight of water; and wherein said material contains at least 1% of a lubricant. |