| abstract |
A tenofovir monobenzyl ester phosphamide compound of the general formula X, and the hydrate, solvate, pharmaceutically acceptable salt thereof or the individual resolved isomer thereof, **(See formula)** wherein Z is selected from O, S, Se , NH- or CH2-, R1, R2, R3, R4, and R5 are each independently selected from H, substituted or unsubstituted C1-C10 linear alkyl, C3-C10 branched alkyl, C3-C10 cycloalkyl, and C6-C10 aryl or heteroaryl, wherein the substitution is from one to three heteroatoms independently selected from O, S, N and Se. |