Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_87a863132c68cf0f62015bbd5d05ab38 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-41 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H13-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0036 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H3-06 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07G3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-18 |
filingDate |
2009-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2021-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45d4a63e82887b11ebf40e4337ba26e0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d3a62a5815871e82103d249dcbe00eed |
publicationDate |
2021-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
ES-2805964-T3 |
titleOfInvention |
Compositions of galactose alpha (1-3) galactose |
abstract |
A method for producing a homogeneously alpha-galactosylated antibody preparation producing an alpha-galactosylated oligosaccharide structure comprising a terminal Gal-alpha (1,3) -Gal-beta (1-4) GlcNAc in an antibody wherein the method comprises : (a) mixing an antibody, an activated galactose, a divalent metal selected from the group consisting of Mn2 +, Ca2 + and Zn2 +, an alpha (1-3) galactosyltransferase, and a beta (1-4) galactosyltransferase in an aqueous medium within a single vessel for forming an aqueous reaction medium; and (b) maintaining said aqueous reaction medium at a pH of 5 to 10 at a temperature of from about 25 ° C to about 40 ° C for a period of time sufficient for said antibody to glycosylate. |
priorityDate |
2008-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |