http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2805802-T3
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5115 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5146 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5192 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 |
filingDate | 2014-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b6fd4a7873ab1c5078abb3c9a50ae50f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d1c05d39d38318a4fd94c476296cdf1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a004a9a7b9cfc3de7671e3e4e9c278a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc06739e113d615e04282bad98ae35e9 |
publicationDate | 2021-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-2805802-T3 |
titleOfInvention | Nanoscale coatings for encapsulation of biological entities |
abstract | A method of producing a bioactive payload delivery device, comprising: forming an intermediate structure by attaching a polymeric material that exhibits a first electrical charge to a virus or viral vector that exhibits a second electrical load different from the first load electrical based on electrostatic force, wherein the intermediate structure formed includes a plurality of regions exhibiting a net surface charge; and forming a coating structure of a biocompatible material directly on the intermediate structure formed to encapsulate the virus or viral vector, in which the coating structure preserves the biological activity of the virus or viral vector encapsulated therein, which produces in this way a bioactive payload delivery device, wherein the formation of the intermediate structure includes reacting the virus or viral vector with a polycationic polymeric material to form a positively charged surface in the plurality of regions of the intermediate structure, and wherein forming the coating structure includes a charge-mediated sol-silica gel condensation reaction directly on the surface of the intermediate structure, wherein the coating structure formed includes an enveloping matrix of silica gel that encapsulates the virus or viral vector. |
priorityDate | 2013-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 50.