abstract |
A composition for use in a method of treating ocular inflammation in a subject in need thereof, the method comprising administering to the subject a therapeutically effective amount of the composition, wherein the composition comprises: a fragment of kemerin having the sequence of YFPGQFAFS (SEQ ID NO .: 2) or a kemerin analog having the sequence Y * FLPS * QFA * -Tic-S (SEQ ID NO .: 3), * denoting D amino acids, where Tic represents acid 1 2,3,4-tetrahydroisoquinoline-3-carboxylic acid; a lipid entity linked to the kemerin fragment or kemerin analog; and optionally a linker that connects the lipid entity to the kemerin fragment or kemerin analog. |