abstract |
A compound of formula (II) for use in a method of treatment or prophylaxis of a tauopathy condition or a tau protein aggregation disease: ** (See formula) ** wherein: X- is a counterion; Y is O and Z is N -R1 and -R2 are each independently saturated C1-6 alkyl, or R1 and R2, together with the nitrogen atom to which they are attached, form a saturated C3-7 heterocycle; -R3 and -R4 are each independently saturated C1-6 alkyl, or R3 and R4, together with the nitrogen atom to which they are attached, form a saturated C3-7 heterocycle; and - -R7 and -R8 are independently selected from: -H, saturated C1-4 alkyl, C2-4 alkenyl and halogenated C1-4 alkyl. |