| abstract |
Follicle-stimulating hormone (FSH) ligand that enhances the bioactivity of FSH, luteinizing hormone (LH) and chorionic gonadotropin (CG), characterized in that said ligand is an antibody or a fragment thereof, and because: the variable domain of the chain heavy contains the following CDRs: - VH-CDR1, defined by the sequence GFTFSDFY (SEQ ID NO: 9); - VH-CDR2, defined by the sequence SRNKAKDYTT (SEQ ID NO: 10); - VH-CDR3, defined by the sequence ARDARFAY (SEQ ID NO: 11); and the variable domain of the light chain contains the following CDRs: - VL-CDR1, defined by the sequence QSLLYSSNQKNY (SEQ ID NO: 12); - VL-CDR2, defined by the sequence WAS; - VL-CDR3, defined by the sequence QQYYSYPRT (SEQ ID NO: 13). |